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Differin (adapalene) Gel, 0.1% is a retinoid used to treat acne. Differin Gel is available in generic form. Common side effects of Differin Gel include a brief sensation of warmth, stinging, tingling, or irritation immediately after applying the medication.

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What is Differin? How Does it Work? Differin Gel (adapalene 0.1%) is the first and only retinoid available OTC for the treatment of acne. A retinoid is simply a derivative of vitamin A

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